Is it Possible to Replace Fentanyl in Anesthesia for Minor Procedures?

Ain Shams University120 enrolled

Overview

To compare between fentanyl group and ketamine lidocaine group for induction of anesthesia as regards hemodynamics and smooth intubation.

Two groups each with 60 patients Group I anesthesia initiated by propofol, fentanyl and cisatracurium. Group II anesthesia initiated by ketamine, lidocaine, propofol and cisatracurium.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

120

Conditions

Anesthesia

Interventions

KetamineDRUG

ketamine

PropofolDRUG

propofol

FentanylDRUG

fentanyl

CisatracuriumDRUG

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * ASA I and II between * Age between 18-55 years * Undergoing minor surgical procedure less than an hour. Exclusion Criteria: * Patients with hypertension * Patients with Ischemic heart diseases * Patients with chronic renal or liver diseases

Locations (1)

Ain Shams University hospitals

Cairo, Egypt

Outcomes

Primary Outcomes

Intubation with less hemodynamic changes

changes in blood pressure with intubation

Time frame: 15 minutes after induction of anesthesia.

Smooth Maintenance of anesthesia

changes in blood pressure during anesthesia

Time frame: anesthesia time

less postoperative pain killers

amount of pain killers used and timing

Time frame: 24 hours postoperative

Intubation with less hemodynamic changes

changes in pulse rate during anesthesia

Time frame: Anesthesia time

Data from ClinicalTrials.gov

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