Development and Needs Assessment and Efficiency of Smart Communication System for Patients With ALS (Part 2)

Inclusion Criteria: * Escorial revised criteria (Brooks et al., 2000),The diagnosis of ALS requires: (A) the presence of: * (A:1) evidence of lower motor neuron (LMN) degeneration by clinical, electrophysiological or neuropathologic examination (A:2) evidence of upper motor neuron (UMN) degeneration by clinical examination, and * (A:3) progressive spread of symptoms or signs within a region or to other regions, as determined by history or examination, together with: (B) the absence of (B:1) electrophysiological or pathological evidence of other disease processes that might explain the signs of LMN and/or UMN degeneration, and (B:2) neuroimaging evidence of other disease processes that might explain the observed clinical and electrophysiological signs. * If they were Taiwanese and used traditional Chinese(Mandarin). * If they were older than age 20 years. Exclusion Criteria: * If they had been diagnosed with frontotemporal dementia, severe depression, or schizophrenia. * If they cannot see the communication board after correction. * If they cannot complete the questionnaire with researchers or family members help.