Treating Acute Pancreatitis With Dabigatran, a Pilot Study

Inclusion Criteria: * Acute Pancreatitis (presence at least two of three features: typical pain, amylase or lipase \>3 times UNL and AP on images) * 18-75 years old * Willingness to sign the informed consent * Symptom onset within 72 hours Exclusion Criteria: * Under 18 years of age or over 75 years of age * Pregnancy or lactating * Presence of pseudo aneurysm on CT * Predicted severe acute pancreatitis * Unwilling or unable to sign the informed consent * Had recent surgery or sphincterotomy * Active pathological bleeding * Concurrent use of anti-coagulation * Known serious hypersensitivity reaction to Dabigatran * CrCI \<30mL/min or on dialysis * Mechanical prosthetic valves * Liver disease * Cancer * On Chemotherapy or immunosuppressant * Persistent ALT, AST, Akl Phos \>2 x ULN * Active hepatitis C, active hepatitis B, and active hepatitis A * Anemia (hemoglobin \<10g/dL) * Thrombocytopenia * Concomitant use of P-gp inhibitors