Optical Coherence Tomography Guided Percutaneous Coronary Intervention for Drug-eluting In-stent Restenosis

Inclusion Criteria: * Age 18 years or older * Patients with angina or evidence of myocardial ischaemia * Patients with restenotic lesions in a previously DES area of a coronary artery * Patients suitable to receive any types of percutaneous coronary intervention (including balloon angioplasty and stent implantation) * The stent diameter of DES-ISR is 2.5mm to 4.0mm * Target lesion length \< 30mm * Target lesion stenosis ≥ 70% diameter stenosis on visual assessment, or ≥ 50% diameter stenosis and with evidence of myocardial ischaemia ischemic Exclusion Criteria: * Patients with acute myocardial infarction with 1 week * Patients with evidence of extensive thrombosis in the target vessel * Patients with left main coronary artery disease * Patients with cardiogenic shock, left ventricular ejection fraction \< 40%,significant renal dysfunction and severe heart valve disease * Patients who had cerebral stroke within 6 months before PCI * Patients with a life expectancy \< 1 year * Patients not able to adhere to follow-up visits