The Effect of 12-week Dietary Intake of Syrup Containing CoQ10 and Collagen on Dermis Density and Other Skin Parameters

Inclusion Criteria: * Caucasian female volunteers aged between 40 and 65 years at the time of the signature of Informed consent form (ICF), * Signed Informed consent form (ICF), * Fitzpatrick skin phototypes II and III, * Signs of skin aging, * In good health condition, * Willingness to avoid a consumption of any food supplements containing CoQ10 and other antioxidants, collagen or vitamins during the study, * Willingness to follow all study procedures and keeping a diary during the study (to follow their compliance and palatability). Exclusion Criteria: * Pregnancy or breastfeeding, * Known or suspected allergy to any ingredient of the tested products, * Changes in dietary habits and dietary supplementation in last three months prior to inclusion, * Regular use of food supplements containing CoQ10 or other antioxidants, collagen or other protein-based food supplements, vitamin A, vitamin E or biotin in last three months prior to inclusion, * Veganism, * Changes in cosmetic facial and body care routine in last month prior to inclusion, * Diagnosed and uncontrolled/untreated/unregulated disease, * Any clinically significant history of serious metabolic disease, digestive tract disease, liver disease, kidney disease, haematological disease, * Acute skin diseases, * Skin pigmentation disorders, * Increased cholesterol and use of cholesterol lowering drugs (statins), * Anticipated sunbathing or solarium visits before or during the study, * Invasive rejuvenation treatments (e.g. needle rollers, needle mesotherapy, deep/medium-deep chemical peels etc.) in last 6 months prior to study entry, * Non-invasive rejuvenation treatments (e.g. radiofrequency, electrotherapy, ultrasound therapy) in last 2 months prior to study entry, * Mental incapacity that precludes adequate understanding or cooperation.