Lactated Ringer's and PlasmaLyte in Critically Ill Adults

West China Hospital12,000 enrolled

Overview

In recent years, there has been a large amount of literature reports that normal saline can increase the incidence of renal injury in critically ill patients compared with balanced salt solution.However, no studies have compared the effects of different types of balanced salt solutions on the incidence of renal injury.

Study Type

OBSERVATIONAL

Enrollment

12,000

Conditions

Critical Illness

Interventions

RLDRUG

lactated Ringer's

PLADRUG

PlasmaLyte

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All patients admitted to ICU Exclusion Criteria: * Patients \<18 year old when admission * Patients who stay less than 24 hours in ICU * Patients who do not sufficient data for further analysis * Readmission patients during the study period

Locations (1)

Department of Critical care medicine of West China Hospital

Chengdu, Sichuan, China

Outcomes

Primary Outcomes

The incidence of acute kidney injury

Time frame: from admission to 28 days

Secondary Outcomes

the incidency of CRRT events

Time frame: from admission to 28 days

the ventilation free days

Time frame: from admission to 28 days

the vasopressure free days

Time frame: from admission to 28 days

Data from ClinicalTrials.gov

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