Efficacy and Safety of Leningrado Association in the Treatment of Hypertension

Inclusion Criteria: * Participants aged 18 years or more; * Participants diagnosed with hypertension (mild to moderate), mild to moderate cardiovascular risk, not controlled by monotherapy and/ or lifestyle modification; Exclusion Criteria: * Any clinical and laboratory findings that, in the judgment of the investigator, may interfere with the safety of research participants; * BP ≥ 180/110 mmHg; * Participants with BMI (body mass index) ≥ 40 Kg/m2; * Previous diagnosis of secondary hypertension; * History of taget organ damage; * History of cardiovascular, hepatic and renal disease; * History of gout, diabetes mellitus and hypokalemia; * Current medical history of cancer; * Current smoking; * History of alcohol abuse or drug use; * Pregnancy or risk of pregnancy and lactating patients; * Known allergy or hypersensitivity to the medicines components used during the clinical trial; * Participation in clinical trial in the year prior to this study.