Surgical Treatment of Periimplantitis in Patients With Risk Factors

Luiz Antonio Pugliesi Alves de Lima40 enrolled

Overview

This study evaluates clinical and radiographic parameters among riks factor groups in patients with periimplantitis. This study will also treat and evaluate the patients response before and after surgical treatment.

Periimplantitis (PI) is an inflammatory process that results in tissue attachment bone loss around the implant. Periodontal disease, smoke habit and type 2diabetes mellitus have been recognized as potential risk factor indicators that might lead to complications establishment and progression around dental implants. PI treatment predictability has been shown limited and influenced by factors not totally clarified. The aim of this study is to evaluate the reparative response after PI surgical treatment at clinical and radiographic levelsin risk factors patients: type 2 diabetes mellitus, smokers and chronic periodontal disease.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Peri-Implantitis Type 2 Diabetes Mellitus Smoking, Cigarette Periodontal Diseases

Interventions

Non-Surgical treatmentPROCEDURE

Implant and teeth surfaces decontamination through scaling and planning, Curettage, profilaxys and Oral Hygiene orientation

Surgical TreatmentPROCEDURE

Anaesthesia, Incision, curettage, Treatment of the contaminated implant surface, Irrigation with saline, Guided Bone Regeneration and suture

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Implants diagnosed with peri-implantitis with boné defects; Probing depth ≥ 4mm; Positive Bleeding on Probing and Suppuration score; Radiographic Bone Loss ≥ 3mm; Generalized Chronic Periodontitis (Armitage, 1999); Heavy Smokers (\> 10 cigarets per day); Type 2 Diabetes Mellitus tipo 2 (ADA, 2005) with HbA1c between 6.5% and 7.5% Exclusion Criteria: Complete Edentulism; Mucosal disease; Alcohol abuse; Systemic disease except type 2 Diabetes Mellitus, that might interfere in periimplantitis progression; Medication intake: anticoagulants, antineoplasics, contraceptives, bisphosphonates and antidepressives; Medication intake in the last 6 months: antibiotics; Medication intake in the last 3 months: antiinflammatories; Aggressive Periodontitis and Anaphylactic shock history; Periodontal treatment in the last 6 months before the baseline; Periodontal Pockets \> 7mm; Light Smokers (\< 10 cigarets/day); Implant Mobility.

Locations (1)

Faculdade de Odontologia Universidade de Sao Paulo

São Paulo, São Paulo, Brazil

RECRUITING

Outcomes

Primary Outcomes

Radiographic Bone height Gain

Radiographic Bone Height Gain Comparison to baseline 3 months after surgical treatment

Time frame: 3 months

Secondary Outcomes

Periimplant Pocket probing depth

Periimplant probing depth comparison to baseline 3 months after surgical treatment

Time frame: 3 months

Central Contacts

Luiz A Lima, phd

CONTACT

+5511992228876 lapalima@usp.br

Data from ClinicalTrials.gov

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