Assessment of Effect of Rapastinel on Driving Performance

Inclusion Criteria * Participant possesses a valid driver's license and is an active driver. Drives a minimum of 5,000 miles (about 8,000 km) per year for the previous 3 years. * Participant has a regular sleep pattern, is not engaged in shift-work, and in general, has at least 7 hours of sleep each night (bedtime occurs between 21:00 and 24:00 hours). Exclusion Criteria * A history within 2 years of, or current intervention for, a sleeping disorder (including excessive snoring, obstructive sleep apnea) or a chronic painful condition that interferes with the participant's sleep. * A history of difficulty in falling asleep or staying asleep in the previous 3 months that is considered clinically significant by the investigator. * Participant has traveled across 1 or more time zones (transmeridian travel) in the 14 days before study intervention or is expected to travel across 1 or more time zones during the study. * Expected to work on a rotating shift during their participation in the study. * Participant works a night shift.