This study evaluates the continuous femoral block between levobupivacaine 0.125% and ropivacaine 0.2% in patients with proximal femoral fracture.These patients will be divided into 2 groups of 35 patients, one L group (levobupivacaine 0.125%) and one R group (ropivacaine 0.2%) distributed randomly, receiving continuous infusion through patient controlled analgesia (PCA) pump with the following parameters: infusion 5 ml / h, bolus 5 ml, lockout 30 min.
Pain is associated with neurohormonal stress, myocardial ischemia and delayed mobilization, thus being able to increase the hospitalization time and associated with increased postoperative mortality. Regional anesthesia through simple or continuous femoral nerve block are options for analgesia in patients with femoral fracture, as well as analgesia by venous opioids. A potential benefit of regional anesthesia is precisely to avoid the use of opioids and other general anesthetics, which in turn are also closely related to postoperative delirium. Continuous femoral block, since the preoperative period, is associated with the reduction of acute pain and opioid consumption, in patients with femoral neck fractures. There are few studies available in the literature comparing analgesic equipotency between levobupivacaine and ropivacaine in peripheral nerve blocks. In none of them, the peripheral analgesia in the femoral nerve, for proximal femoral fracture was compared.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
70
infusion of anesthetic by PCA pump
Rafael M Linhares
Rio de Janeiro, Brazil
RECRUITINGintensity of individual pain episodes
Self report pain intensity in the preoperative period. Scored 0-10 (0 = no pain; 10 = pain as bad as can be)
Time frame: 6 hours after hospital admission
Number of PCA firing
in each patient at time of evaluation of pain
Time frame: 72 hours
Degree of satisfaction with analgesic therapy
using the 5-point rating scale (very dissatisfied, dissatisfied, neutral, satisfied or very pleased)
Time frame: up to 72 hours - at the moment of surgery; or at the end of 72 hours
Quality of sleep
very good, good, bad and very bad
Time frame: up to 72 hours
the cost of analgesic therapy
including catheters, PCA and medication in each patient
Time frame: up to 72 hours
adverse event
paresthesia, nausea, vomiting, ringing in the ear, metallic taste, convulsion or cardiac arrest
Time frame: up to 72 hours
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.