Natriuretic Peptides After Left Atrial Appendage Amputation

University of Giessen21 enrolled

Overview

Surgical amputation of the left atrial appendage (LAA) is an established intervention during surgical atrial fibrillation (AF) therapy. However, its effects on the endocrine function of the left atrium are unclear. This study aims to quantify the serum levels of natriuretic peptides in patients who undergo concomitant surgical AF ablation with or without LAA amputation.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SCREENING

Masking

TRIPLE

Enrollment

Conditions

Atrial Fibrillation

Interventions

LAA amputationPROCEDURE

complete surgical amputation of the left atrial appendage

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Indication for concomitant AF therapy during cardiac surgery with cardiopulmonary bypass Exclusion Criteria: * Lack of informed consent

Locations (1)

Department of Adult and Pediatric Cardiovascular Surgery

Giessen, Germany

Outcomes

Primary Outcomes

Serum levels of proANP and BNP until 800days post surgery

Time frame: 800days

Data from ClinicalTrials.gov

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