The primary aim of this study is to evaluate whether pulse oximetry based noninvasive hemoglobin (SpHb) monitoring can reduce the incidence of hemoglobin (Hb) level out of the target range in adult patients undergoing major surgery with the potential risk of bleeding.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
130
Noninvasive, continuous pulse oximetry-based hemoglobin (SpHb) monitoring
Conventional management without SpHb monitoring
Seoul national university hospital
Seoul, South Korea
The incidence of deviation from the target hemoglobin range
(The number of laboratory samples with the result hemoglobin concentrations were out of the target range)/(Total number of laboratory samples that performed during intra-operative periods)
Time frame: Until transfer to PACU (Post-Anesthesia Care Unit), from the beginning of the induction of anesthesia
The percentage extent of deviation from the target hemoglobin range
The percentage extent of deviation of laboratory hemoglobin out of the prespecified target range
Time frame: Until transfer to PACU (Post-Anesthesia Care Unit), from the beginning of the induction of anesthesia
Number of Point-of-care (POC) sampling during surgery
Number of Point-of-care (POC) sampling for measurement of hemoglobin concentration. In SpHb group, POC sampling will be done according to SpHb level. In control group, POC sampling will be done at discretion of anesthesiologist.
Time frame: Until transfer to PACU (Post-Anesthesia Care Unit), from the beginning of the induction of anesthesia
Accuracy of the SpHb value
Standard Laboratory hemoglobin measurement will be used as reference. Laboratory measurements will be done every 30 minute during surgery
Time frame: Until transfer to PACU (Post-Anesthesia Care Unit), from the beginning of the induction of anesthesia
Number of patients who receive intra-operative transfusion
Number of patients who were transfused with pRBCs intraoperatively
Time frame: Until transfer to PACU (Post-Anesthesia Care Unit), from the beginning of the induction of anesthesia
Total volume of intravenous fluids given
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Total volume of intravenous fluids given intra-operatively
Time frame: Until transfer to PACU (Post-Anesthesia Care Unit), from the beginning of the induction of anesthesia
Total volume of pRBCs transfused
Total volume of pRBCs transfused intra-operatively
Time frame: Until transfer to PACU (Post-Anesthesia Care Unit), from the beginning of the induction of anesthesia
Time for transfusion delay
Time from the determination of transfusion to actual transfusion, in minutes
Time frame: Until transfer to PACU (Post-Anesthesia Care Unit), from the beginning of the induction of anesthesia
Incidence of intraoperative hypotension
hypotension is defined as SBP \< 80% of baseline SBP
Time frame: Until transfer to PACU (Post-Anesthesia Care Unit), from the beginning of the induction of anesthesia
laboratory total hemoglobin value, at postoperative day 1
total hemoglobin value measured by standard laboratory method
Time frame: at postoperative day 1