Mitral valve reconstruction via minimal invasive antero- lateral thoracotomy is done in cardioplegia with a cardioplegic solution, either HTK-Bretschneider (Custidiol®) (a crystalloid intracellular solution) or St. Thomas (a crystalloid extracellular solution). This study investigates HTK-Bretschneider versus St. Thomas cardioplegic solution regarding peri- and postoperative outcome, especially for cardiac biomarkers.
Study Type
OBSERVATIONAL
Enrollment
200
cardioplegia with HTK-Bretschneider cardioplegic solution
cardioplegia with St. Thomas cardioplegic solution
Klinik für Herzchirurgie, Universitätsspital Basel
Basel, Switzerland
high specific troponin T (hs-TrT) (μg/l)
cardial biomarker for myocardial damage
Time frame: perioperative during minimal invasive surgery
Creatin-Phosphokinase (CK) (U/l)
cardial biomarker for myocardial damage
Time frame: perioperative during minimal invasive surgery
Creatinkinase Muscle- Brain (CK-MB) (U/l)
cardial biomarker for myocardial damage
Time frame: perioperative during minimal invasive surgery
mortality rate
number of deaths
Time frame: from minimal invasive surgery until 30 days post surgery
length of stay in intensive care unit (days)
length of stay in intensive care unit (number of days)
Time frame: from minimal invasive surgery until 30 days post surgery
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