SURESTEP: Transcranial Direct Current Stimulation in Super Refractory Status Epilepticus

N/ATerminatedNCT03819543

University of Manitoba10 enrolled

Overview

The purpose of this study is to determine whether transcranial direct current stimulation affects super refractory status epilepticus.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Status Epilepticus

Interventions

Transcranial Direct Current StimulationDEVICE

Application of transcranial direct current stimulation via scalp electrodes over presumed epileptogenic focus for 20 minutes at 2.0 mA.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * diagnosis of super refractory status epilepticus * admitted to the intensive care unit * identifiable epileptogenic focus on EEG Exclusion Criteria: * contraindications to scalp EEG * lice * scabies * other hair/skin infection * scalp psoriasis * hypersensitivity * other severe dermatological condition * previous adverse reaction to collodion * vagal nerve stimulator * implantable cardioverter defibrillator * cardiac pacemaker

Locations (1)

Health Sciences Centre

Winnipeg, Manitoba, Canada

Outcomes

Primary Outcomes

Frequency of Epileptiform Activity, Per Patient-based

EEG epileptiform activity as defined in units of spikes per second for a given patient. Pre-stim compares spike rates during stimulation to before stimulation. Pre-post compares spike rates after stimulation to before stimulation.

Time frame: Up to 3 hours per EEG recording

Secondary Outcomes

Frequency of Epileptiform Activity, Per-session Based

EEG epileptiform activity as defined in units of spikes per second for a given stimulation session. Pre-stim compares spike rates during stimulation to before stimulation. Pre-post compares spike rates after stimulation to before stimulation.

Time frame: Up to 3 hours per EEG recording

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.