A Study of DE-111A on the Treatment of Open Angle Glaucoma or Ocular Hypertension

Inclusion Criteria: * Diagnosis of open angle glaucoma (including primary open angle glaucoma, exfoliation glaucoma or pigmentary glaucoma) in one or both eyes or ocular hypertension for which the subject has been using prostaglandin or beta-adrenergic blocker IOP (intraocular pressure) -lowering drugs before the screening visit * Those who have signed the informed consent form Exclusion Criteria: * Women who are pregnant, nursing or planning pregnancy, or women of child-bearing potential who are not using a reliable method of contraception * Anterior chamber angle in either eye to be treated with the level \<2 according to Shaffer classification as measured by gonioscopy * Corneal disorder or other disease preventing reliable applanation tonometry in the treated eyes, including refractive surgery of ocular anterior segment) * Alcohol or drug abuse * Current participation in another clinical trial involving an investigational drug/device, or participation in such a trial within 30 days before Screening visit