This research study will examine the feasibility of conducting an eight-week yoga intervention for individuals with chronic painful chemotherapy-induced peripheral neuropathy.
This research study will examine the feasibility of conducting an eight-week yoga intervention for individuals with chronic painful chemotherapy-induced peripheral neuropathy. The investigators will also explore participants' perceptions of acceptability and satisfaction with the yoga intervention. Lastly, the investigators will examine changes in chemotherapy-induced peripheral neuropathy severity, physical function, sleep-related impairment, fatigue, anxiety, depression, and pain following the eight-week yoga intervention.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
47
Participants will attend at least one group class per week (in-person or Zoom) and practice one self-guided yoga video class at home on their own per week, over eight weeks Participants may choose to attend "Flow Yoga" and/or "Chair Flow Yoga" classes. These classes will be videotaped and made available to participants electronically. Classes consist of: * guided breathing exercises, * upper and lower extremity stretching * structured postures and movements to improve balance and strength
Dana Farber Cancer Institute
Boston, Massachusetts, United States
Number of participants recruited to participate in the study
Feasibility of participant recruitment to the study
Time frame: From enrollment to end of treatment at 8 weeks.
Frequency of yoga practice by participants
Feasibility of participant adherence to the yoga intervention
Time frame: From enrollment to end of treatment at 8 weeks.
Frequency of outcome assessments completed by participants.
Feasibility of participant adherence to outcome assessments
Time frame: From enrollment to end of treatment at 8 weeks.
Acceptability and Satisfaction with Participation in Yoga Intervention
We will use semi-structured interviews to gain information about participants' experience with the yoga program
Time frame: At the end of treatment, 8 weeks after enrollment
Worst Chemotherapy-Induced Peripheral Neuropathy Pain Intensity
Change in 0 - 10 numerical rating scale of worst chemotherapy-induced peripheral neuropathy pain (via 7-day pain diary) from enrollment to end of treatment at 8 weeks. Total scores range from 0 - 10, with higher scores representing worse pain.
Time frame: At the time of enrollment and at the end of treatment, 8 weeks after enrollment
Chemotherapy-Induced Peripheral Neuropathy Severity
Change in European Organization of Research and Treatment of Cancer Quality of Life Questionnaire-Chemotherapy-Induced Peripheral Neuropathy Scale-20 score from enrollment to end of treatment at 8 weeks. Total scores range from 0 - 100, with higher scores representing worse chemotherapy-induced peripheral neuropathy severity.
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Time frame: From enrollment to end of treatment at 8 weeks.At the time of enrollment and at the end of treatment, 8 weeks after enrollment
Pain Interference
Change in Patient Reported Outcomes Measurement Information System (PROMIS) Pain Interference 4a score from enrollment to the end of treatment at 8 weeks. Total scores range from 41.6 - 75.6, with higher scores representing worse pain interference.
Time frame: At the time of enrollment and at the end of treatment, 8 weeks after enrollment
Sleep-Related Impairment
Change in Patient Reported Outcomes Measurement Information System (PROMIS) Sleep-related Impairment 8a score from enrollment to the end of treatment at 8 weeks. Total scores range from 30.0 - 80.1 with higher scores representing worse sleep-related impairment.
Time frame: At the time of enrollment and at the end of treatment, 8 weeks after enrollment
Anxiety assessed by the "Change in Patient Reported Outcomes Measurement Information System (PROMIS) Anxiety"
Change in Patient Reported Outcomes Measurement Information System (PROMIS) Anxiety 4a score from enrollment to the end of treatment at 8 weeks. Total scores range from 40.3 - 81.6, with higher scores representing worse anxiety.
Time frame: At the time of enrollment and at the end of treatment, 8 weeks after enrollment
Depression assessed by Change in Patient Reported Outcomes Measurement Information System (PROMIS) Depression
Change in Patient Reported Outcomes Measurement Information System (PROMIS) Depression 4a score from enrollment to the end of treatment at 8 weeks. Total scores range from 41.0 - 79.4, with higher scores representing worse depression.
Time frame: At the time of enrollment and at the end of treatment, 8 weeks after enrollment
Fatigue assessed by Change in Patient Reported Outcomes Measurement Information System (PROMIS) Fatigue
Change in Patient Reported Outcomes Measurement Information System (PROMIS) Fatigue 4a score from enrollment to the end of treatment at 8 weeks. Total scores range from 33.7 - 75.8, with higher scores representing worse fatigue.
Time frame: At the time of enrollment and at the end of treatment, 8 weeks after enrollment
Physical Function
Change in Patient Reported Outcomes Measurement Information System (PROMIS) Physical Function 4a score from enrollment to the end of treatment at 8 weeks. Total scores range from 22.5 - 57.0, with higher scores representing better physical function.
Time frame: At the time of enrollment and at the end of treatment, at 8 weeks.