The Influence of Post-transjugular Intrahepatic Portosystemic Shunt Hepatic Encephalopathy

Inclusion Criteria: 1. The patient's gender is not limited, ≥ 18 years old and ≤ 75 years old; 2. Clinically diagnosed post-hepatitis B cirrhosis; 3. History of esophageal varices venous rupture confirmed by endoscopy, re-bleeding after standard treatment; 4. Liver function Child A or B; 5. Imaging (CT or MRI) suggests that the left/right first branch of the intrahepatic portal can construct a shunt; 6. Platelet count ≥ 50 × 109 / L; 7. Prothrombin time (PT) does not exceed the upper limit of the normal control for 3 seconds; 8. Serum creatinine concentration ≤115umol/L; 9. Patients and their families agree to join the clinical trial and sign an informed consent form. Exclusion Criteria: 1. Imaging confirms portal vein thrombosis; 2. Patients who have undergone previous surgical treatment of portal hypertension (including splenectomy, surgical disconnection or shunt); 3. Combine any malignant tumor; 4. History of previous hepatic encephalopathy; 5. Consolidation of intractable ascites; 6. Pulmonary artery pressure \> 40 mmHg, left ventricular ejection fraction \< 50%, congestive heart failure or severe valvular insufficiency; 7. Others: persistent active bleeding, vital signs can not be maintained, blood ammonia ≥ 100, total bilirubin \> 51umol / L failed to improve after symptomatic treatment; combined active infection, especially biliary system inflammation; female patients are pregnant Or lactation; severe contrast allergy.