This study was conducted to investigate the effects of daily supplementation of Soybean germ extract on decrease of body fat
This study was a 12 weeks, randomized, double-blind, placebo-controlled human trial. 80 subjects were randomly divided into Soybean germ extract 1,600 mg or placebo group. The investigators measured Body Fat Mass, Percent Body Fat, Fat Free Mass, weight, and body mass index, etc.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
80
Soybean Germ Extract 1,600 mg/day for 12 weeks.
Placebo 1,600 mg/day for 12 weeks.
Clinical Trial Center for Functional Foods Chonbuk National University Hospital
Jeonju, Jeollabuk-do, South Korea
RECRUITINGChanges of body fat mass
Body fat mass was measured in study baseline and 12 week
Time frame: Baseline and 12 week
Changes of percent body fat
Measurement is made using dual energy X-ray absorptiometry (DEXA / Hologic Discovery, USA). Left arm, right arm, left leg, right leg, trunk, total will be report percent body fat in %.
Time frame: Baseline and 12 week
Changes of fat free mass
Measurement is made using dual energy X-ray absorptiometry (DEXA / Hologic Discovery, USA). Left arm, right arm, left leg, right leg, trunk, total will be report fat free mass in g.
Time frame: Baseline and 12 week
Changes of Anthropometric indicate: body weight
Anthropometric indices were measured in study screening, baseline and 12 week. Body weight in kg.
Time frame: Screening, baseline and 12 week
Changes of Anthropometric indicate: body mass index
Anthropometric indices were measured in study screening, baseline and 12 week. Weight/height\^2 will be report body mass index in kg/m\^2.
Time frame: Screening, baseline and 12 week
Changes of Anthropometric indices: waist circumference, hip circumference
Anthropometric indices were measured in study screening, baseline and 12 week. Waist circumference, hip circumference in cm.
Time frame: Screening, baseline and 12 week
Changes of Anthropometric indicate: waist -hip circumference ratio
Anthropometric indices were measured in study screening, baseline and 12 week. Waist circumference/hip circumference will be report waist -hip circumference ratio.
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Time frame: Screening, baseline and 12 week
Changes of lipid metabolism indicators: Total cholesterol, Triglyceride, LDL-cholesterol, HDL-cholesterol
Lipid metabolism indicators(mg/dL) were measured in study baseline and 12 week.
Time frame: Baseline and 12 week
Changes of obesity-related hormones indicators: Adiponectin, Leptin
obesity-related hormones indicators were measured in study baseline and 12 week
Time frame: Baseline and 12 week
Changes of energy expenditure Indicators: Uncoupling protein-1(UCP-1), Peroxisome proliferator-activated receptor gamma coactivator-1 α(PGC-1 α)
energy expenditure Indicators were measured in study baseline and 12 week
Time frame: Baseline and 12 week