secondary spontaneous pneumothorax patients will be enrolled ,all of them will receive PRP with different doses and schedules
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
40
Application of platelet rich plasma through the intercostal tube into the pleural space
Zagazig University Faculty of medicine Chest Department
Zagazig, Asharqia, Egypt
RECRUITINGAir leak assessment by Cerfolio classification of the air leak by single observer
Continuous:Air leak is Present throughout the respiratory cycle Inspiratory : Present during the inspiration phase of the respiratory cycle. Expiratory: Present only during the expiratory phase of the respiratory cycle Forced expiration: Present only when the patient coughs or forces exhalation
Time frame: within 10 days after application of platelet rich plasma
physician assessment of complete lung inflation by absence of signs of pneumothorax in chest x ray done to the patient during hospital stay
no Chest x ray signs of pneumothorax i.e no jet balck translucency or border of collapsed lung) by physician interpretation
Time frame: within 10 days after application of platelet rich plasma
recurrence of pneumothorax by physician interpretation of Chest x ray done to the patient in follow up visit i.e detecting jet balck translucency or border of collapsed lung
no Chest x ray signs of pneumothorax i.e no jet balck translucency or border of collapsed lung) by physician interpretation
Time frame: one month after removal of intercostal tube
recurrence of pneumothorax by physician interpretation of Chest x ray done to the patient in follow up visit i.e detecting jet balck translucency or border of collapsed lung
no Chest x ray signs of pneumothorax i.e no jet balck translucency or border of collapsed lung) by physician interpretation
Time frame: two months after removal of intercostal tube
recurrence of pneumothorax by physician interpretation of Chest x ray done to the patient in follow up visit i.e detecting jet balck translucency or border of collapsed lung
no Chest x ray signs of pneumothorax i.e no jet balck translucency or border of collapsed lung) by physician interpretation
Time frame: three months after removal of intercostal tube
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recurrence of pneumothorax by physician interpretation of Chest x ray done to the patient in follow up visit i.e detecting jet balck translucency or border of collapsed lung
no Chest x ray signs of pneumothorax i.e no jet balck translucency or border of collapsed lung) by physician interpretation
Time frame: six months after removal of intercostal tube