Aim of the study is to investigate health effects of oats and oat derived components, in human intervention studies, with the purpose to build new knowledge for development of cardiometabolic protective foods.
The overall goal is to increase the knowledge which can be used for the development of food products with anti-diabetic properties, with the purpose to facilitate healthier food choices for people. More specifically the primary purpose of this project is to evaluate effects in healthy humans on cardiometabolic test markers of oat and oat based product. The new knowledge will form a base for the development of oat based food products with added health values.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
24
Oat based beverage with added different concentration of extracted oat component.
Oat based beverage with added different concentration of extracted oat component.
Oat based beverage with added different concentration of extracted oat component.
Food Technology, engineering and Nutrition, LTH, Lund University
Lund, Sweden
Blood glucose regulation
Postprandial blood glucose regulation (incremental area under the curve) acute after intake of the test products and at forthcoming meals within 5.5 hours after consumption of test products.
Time frame: 0 - 5.5 hours ( at fasting and then repeatedly after breakfast and Standardize lunch)
Serum insulin
Acute effects of postprandial serum insulin concentrations (incremental area under the curve) after intake of the test products.
Time frame: 0 - 5.5 hours ( at fasting and then repeatedly after breakfast and Standardize lunch)
plasma GLP-1 (glucagon-like peptide-1 )
Gastro-intestinale hormones involved in appetite and metabolic regulation
Time frame: 0 - 5.5 hours ( at fasting and then repeatedly after breakfast and Standardize lunch)
IL (interleukin)-6
Inflammatory markers in blood
Time frame: 0 - 5.5 hours ( at fasting and then repeatedly after breakfast and Standardize lunch)
Plasma PYY (peptide tyrosine tyrosine)
Gastro-intestinale hormones involved in appetite and metabolic regulation
Time frame: 0 - 5.5 hours ( at fasting and then repeatedly after breakfast and Standardize lunch)
IL- 1beta
Inflammatory markers in blood
Time frame: 0 - 5.5 hours ( at fasting and then repeatedly after breakfast and Standardize lunch)
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Oat based beverage with added different concentration of extracted oat component.
Glucose based beverage without added test components is used as control product