Effects of E-Cigarette Power and Nicotine Content in Dual Users and Vapers

Virginia Commonwealth University48 enrolled

Overview

This study aims to understand the effects of device power and nicotine concentration on the likelihood that someone would use or abuse e-cigarettes.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

Electronic Cigarettes

Interventions

E-cigarette Lab Session 15 watts, 10 mg nicotineOTHER

E-cigarette paired with low nicotine, low device power

E-cigarette Lab Session 15 watts, 30 mg nicotineOTHER

E-cigarette paired with low nicotine, low device power

E-cigarette Lab Session 30 watts, 10 mg nicotineOTHER

E-cigarette paired with low nicotine, low device power

Eligibility

Sex: ALLMin age: 21 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy (determined by self-report) * between the ages of 21-55 * willing to provide informed consent * able to attend the lab and abstain from tobacco/nicotine as required and must agree to use designated products according to study protocol Exclusion Criteria: * Women if they are breast-feeding or test positive for pregnancy (by urinalysis) at screening. Some study details about the eligibility criteria are purposely omitted at this time to preserve scientific integrity. Full details will be posted at the conclusion of the study.

Locations (1)

Center for the Study of Tobacco Products

Richmond, Virginia, United States

Outcomes

Primary Outcomes

Breakpoint of Drug Purchase Tasks (DPT)

The DPTs will yield measures of willingness to pay and measures of price sensitivity for session-specific tobacco products. Choices made during this task are not reinforced during the session. Each DPT will be completed once per study session (either 90 minutes or approximately 180 minutes into the session, timing varies based on task order presentation and potentially choices made in tasks presented prior to this task).

Time frame: Up to 180 minutes

Breakpoint of Multiple Choice Procedure (MCP)

The MCP will yield of measure of willingness to pay for session-specific tobacco products. One choice made during this task is reinforced (i.e., money or tobacco product is distributed). Completed once per study session (either 90 minutes or approximately 180 minutes into the session, timing varies based on task order presentation and potentially choices made in tasks presented prior to this task).

Time frame: Up to 180 minutes.

Effort for Product Puffs With the Progressive Ratio Task (PRT)

The PRT will yield a measure of willingness to work for session-specific tobacco products (via number of times a space bar is pressed to earn puffs) by measuring the number of puffs self-administrated. Completed once per study session (either 90 minutes or approximately 180 minutes into the session, timing varies based on task order presentation and potentially choices made in tasks presented prior to this task).

Time frame: Up to 180 minutes.

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.