The aim of this study is to compare the effects of Ivabradine and metoprolol to reduce heart rate prior to coronary CT angiography in patients with advanced heart failure.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Enrollment
200
7.5 mg oral single dose if the heart rate would not reach to 60/minute then give another dose, 7.5 mg
5 mg oral single dose if the heart rate would not reach to 60/minute then give another dose, 5 mg
Ahmad Amin
Tehran, Iran
RECRUITINGHeart rate
Changing heart rate during imaging study
Time frame: 30 minutes before and after coronary CT angiography
Dyspnea
Shortness of breath, or "dyspnea", is the most famous symptom of left ventricular failure. It typically appears during strenuous activities, and progresses to ordinary activities, less than ordinary activities and ultimately resting state. The severity is categorized as above (FC 1 to 4)
Time frame: 30 minutes before and after coronary CT angiography and 6 months later
Functional calss
Heart Failure severity has been classified according to New York Heart Association (NYHA) to: * Class I: No limitation of physical activity. Ordinary physical activity does not cause symptoms of HF. * Class II: Slight limitation of physical activity. Comfortable at rest, but ordinary physical activity results in symptoms of HF. * Class III: Marked limitation of physical activity. Comfortable at rest, but less than ordinary activity causes symptoms of HF. * Class IV: Unable to perform any physical activity without symptoms of HF, or symptoms of HF at rest.
Time frame: 30 minutes before and after coronary CT angiography and 6 months later
Blood pressure, systolic and diastolic
The amount of blood pressure measured by sphygmomanometer
Time frame: 30 minutes before and after coronary CT angiography and 6 months later
Sleep quality
The rate of disturbed sleep measured as better than before, Worse than before, and No change There are no standard classification for severity of this symptom. In our study, we measure this symptom as : * Better than before (1) * Worse than before (2) * No change (0)
Time frame: Before CT angiography and 6 months later
Appetite
The rate of changing in appetite level measured as better than before, Worse than before, and No change Loss of appetite is a common symptom of heart failure. There are no standard classification for severity of this symptom. In our study, we measure this symptom as : * Better than before (1) * Worse than before (2) * No change (0)
Time frame: Before CT angiography and 6 months later
Prolonged bradycardia
Persistence of Bradycardia more than 6 hours is called prolonged bradycardia.
Time frame: 30 minutes before and after coronary CT angiography
Hypotension
Systolic less than 80 mm Hg
Time frame: 30 minutes before and after coronary CT angiography
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