Analysis of the Impact of Cholecystectomy on Gut Microbiome in Adults

Inclusion Criteria: 1. Gallbladder polyps diameter mm \>10; 2. The history of the symptoms of patients with gallbladder stones, there was no history of acute attack in the past month; 3. Age \<70 years old; 4. No serious systemic diseases such as diabetes, hypertension, heart disease, lung disease and so on/American anesthesia Association (ASA) grade I or II; 5. BMI\<30; 6. Families have better care and observation, and away from the hospital within 1 hours; patients and their families understand the process of ambulatory surgery (24 hours) and the pros and cons. Exclusion Criteria: 1. Less than 18 years old; 2. With previous gastric surgery ; 3. Major systemic diseases ; 4. Pregnancy or lactation; 5. The use of antibiotics or yogurt within 2 months before the study.