Maternal and Perinatal Pregnancy Outcome in Women With Heterozygous Hemoglobinopathies

University Hospital, Basel, Switzerland540 enrolled

Overview

This retrospective study aims to investigate pregnancy outcome in women with heterozygous hemoglobinopathies (regarding gestational diabetes, cholestasis and urinary tract infections) and to analyze if there are aggravated maternal and/or perinatal risks.

Study Type

OBSERVATIONAL

Enrollment

540

Conditions

Heterozygous Haemoglobinopathy

Interventions

pregnancy outcomeOTHER

descriptive statistics of variables

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * pregnant women with or without heterozygous hemoglobinopathy Exclusion Criteria: * refusal of study participation

Locations (2)

Frauenklinik University Hospital Basel

Basel, Switzerland

Frauenklinik University Hospital Zürich

Zurich, Switzerland

Outcomes

Primary Outcomes

gestational diabetes

number of women developing gestational diabetes in pregnancy

Time frame: in the course of pregnancy until delivery

cholestasis in pregnancy

number of women developing cholestasis in pregnancy

Time frame: in the course of pregnancy until delivery

urinary tract infection

number of women developing urinary tract infection

Time frame: in the course of pregnancy until delivery

Data from ClinicalTrials.gov

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