An observational double-blind cohort study that examined the association between HCV viral hepatitis, blood sugar level and systolic blood pressure in the Egyptian population
a cohort study on greater than 70000 Egyptian patients had been conducted. for all patients,1- we detected the Hepatitis C Virus (HCV) RNA antigens ( hepatitis C virus)presence using BIOLINE HCV kits( qualitative test for diagnosis of hepatitis C virus in the blood), For all positive patients, confirmatory rapid screening test was performed and all patients who tested positive twice underwent a qPCR test using QIAampMinElute Virus Spin kit (Thermo Fisher Scientific, Waltham, MA, USA) performed according to the manufacturer's recommended protocol. 2- Investigators measured blood sugar levels for each patient using ACCU-CHEK kits(finger stick sugar level measurement) 3- Measured systolic blood pressure for each patient was measured using mercury meters. 4-for all patients investigators obtained full medical history regarding the presence or absence of chronic diabetes, chronic hypertension, coronary artery disease, kidney impairment with dialysis or chronic obstructive pulmonary disease. 5- for all patients investigators listed age, gender, and body mass index. 66121 patients were negative for HCV and 4852 were positive for HCV. Investigators measured the association between HCV presence, high blood sugar levels and high systolic blood pressure. It is supposed that this is the largest study in the world that examined both associations. In a word, this study was responding to a specific question: is hepatitis c virus presence is associated with high blood pressure or high sugar level or both or not associated???
Study Type
OBSERVATIONAL
Enrollment
71,975
We used BIOLINE HCV kits to detect the presence of HCV antibodies in stick blood samples of all recruited patients.
For all patients, we measured random blood sugar levels by stick blood samples using ACCU-CHEK kits.
For all patients, we measured systolic blood pressure using ErKameter 3000 mercury manometer.
Egyptian Ministry of Health
Asyut, Egypt
HCV diagnosis
Detection of patients who are HCV positive or negative
Time frame: 20 minutes
Measurement of blood sugar level in mg/dl
Detection of the percentage of patients with high blood sugar level in HCV positive or negative patients
Time frame: 1 minute
Measurement of systolic blood pressure in mmHg
Detection of the percentage of patients with high systolic blood pressure in HCV positive or negative patients
Time frame: 1 minute
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