Lung cancer is the leading cause of cancer related mortality. Among them, non small cell lung cancer accounts for 85%. Only part of patients could be treated with radical surgery. Mitochondria-targeted system therapy combined with radiofrequency ablation could be an alternative treatment. Small sample clinical cases verified that this therapy could be an efficacy and safe treatment in a short period. The primary aim of this trial is to determine if the efficacy of mitochondria-targeted system therapy combined with radiofrequency ablation is comparable to that of standard surgical interventions for patients with non-small cell lung cancer.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
1,753
Patients will be treated with mitochondria-targeted system therapy and radiofrequency ablation in the primary tumor sites
Patients will be treated with surgery
Shanghai 10th People's Hospital
Shanghai, Shanghai Municipality, China
RECRUITINGDisease-free survival
Time frame: From the date of randomization until the date of first documented progression,assessed up to 60 months
Overall survival
Time frame: From the date of randomization until the date of death from any cause,assessed up to 60 months
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