COmpartment Syndrome vaLidation Of Non Invasive Assessment of Tissue Pressure

University Hospital, Angers100 enrolled

Overview

Chronic Compartment Syndrome (CCS) is a pathology that affects more specifically subjects exposed to repeated movements, particularly in a professional life or sports. The diagnosis is difficult and often delayed. Currently, the reference technique is invasive. It consists of measuring by a intramuscular puncture (IMP) pressure in the offending compartment early after effort (usually between 1 and 5 minutes post-exercise). A value greater than or equal to 30 mmHg in the first 5 minutes is used as a diagnostic criterion for CCS. Other less invasive techniques (scintigraphy) exist but are subject to certain discordances of interpretation. The advent of new assessment tools, like the MyotonPRO, pave the way for a non-invasive diagnostic approach.

Patients referred for suspected chronic compartment syndrome causing will be included. After signing the consent, the subject will have a clinical and paraclinical examination. Age, sex, height, weight, side of clinical symptomatology will be collected. Medical history current treatments will also be noted. Once the consent is collected, the patient performs, according to the data of the literature and service habits a stress test aimed at triggering the painful symptomatology associated with post-exercise IMP and MyotonPRO measurements as the same time.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

100

Conditions

Compartment Syndrome

Interventions

MyotonPRODIAGNOSTIC_TEST

Each patient will perform a stress test to trigger the painful. Measurements will be done by intramuscular punction as usually, and by non invasive tool : MyotonPRO

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Affiliation to the French National healthcare system * French speaking patients * Referred for investigation of compartment syndrome causing Exclusion Criteria: * Pregnancy * Inability to understand the study goal * Patients protected by decision of law * Extended dermatosis * Coagulation disorder

Locations (1)

Centre hospitalier universitaire

Angers, France

Outcomes

Primary Outcomes

Diagnostic performance of MyotonPRO

To study the diagnostic performance of tissue stiffness measurement by MyotonPRO at 1 minute post-exercise in patients suspected of anterolateral of leg

Time frame: 3 years

Secondary Outcomes

Diagnostic performance of MyotonPRO at 1 minute post-exercise

To study the diagnostic performance of the MyotonPRO tissue stiffness measurement variation between rest and 1 minute post-exercise.

Time frame: 3 years

Diagnostic performance of MyotonPRO at 5 minute post-exercise

To study the diagnostic performance of the MyotonPRO tissue stiffness measurement variation between rest and 5 minute post-exercise.

Time frame: 3 years

Data from ClinicalTrials.gov

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