Study on Prediction of Left Ventricular Remodeling Using ST2

Keimyung University Dongsan Medical Center114 enrolled

Overview

Patients who underwent percutaneous coronary intervention after diagnosis of acute coronary syndrome should be enrolled in the study and follow - up.

Obtain written consent for patients who meet all of the selection criteria and who do not meet the exclusion criteria. ACS(Acute Coronary Syndrome) patients with LV systolic dysfunction(LVEF\<50%) on TTE test who underwent successful PCI. At that time, patient proceed with the Baseline blood test(ST2) in hospital. And then, Medical therapy for 3 months later patient proceed with the Follow-up blood test(ST2) and TTE in OPD.

Study Type

OBSERVATIONAL

Enrollment

114

Conditions

Acute Coronary Syndrome

Eligibility

Sex: ALLMin age: 19 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Subjects aged 19 or older * Patients with acute coronary syndrome who underwent successful percutaneous coronary intervention * Patients with left ventricular ejection fraction less than 50% on transthoracic echocardiography * Patients who voluntarily agreed to participate in the study Exclusion Criteria: * Failure to obtain TIMI 3 flow after procedure * If the remaining life span is less than one year * Women who are breastfeeding or plan to become pregnant or are planning to become pregnant during the study period

Locations (1)

Keimyung University Dongsan Hospital

Daegu, Dalseogu, South Korea

Outcomes

Primary Outcomes

ST2 and LV end-diastolic volume index

the correlation between changes of ST2 and LV end-diastolic volume index

Time frame: 3 months

Secondary Outcomes

ST2 and LV ejection fraction

the correlation between changes of ST2 and LV ejection fraction

Time frame: 3 months

ST2 and E over e' ratio

the correlation between changes of ST2 and E over e' ratio

Time frame: 3 months

ST2 and LV wall motion score

the correlation between changes of ST2 and LV wall motion score

Time frame: 3 months

Data from ClinicalTrials.gov

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