Hypofractionated Radiotherapy for Recurrent DIPG

Inclusion Criteria: 1. Patients must be ≤30 years of age 2. Patients must have a diagnosis of progressive DIPG. 3. Received prior IMRT based definitive radiotherapy to a dose of ≥54 Gy. 4. The patient and or parent/legal guardian must be physically and mentally capable of signing the consent form of their own volition. 5. Steroids dosage must be unchanged for 5 days. 6. No Bevacizumab within 21 days (Half-life 11 days \~) Exclusion Criteria: 1. Patients with incomplete medical records 2. Patients with prior history of reirradiation for DIPG 3. Life expectancy \< or equal to 1 month 4. Pregnant women 5. Age \>30 6. Prisoners 7. Concurrent systemic therapy at the time of reirradiation 8. Physically or mentally incapable of signing the consent form of their own volition 9. \< 6 mos time interval between completion of initial RT to start of reRT.