France is the country of Europe where the prevalence of pregnant women smokers is the highest (35.9% before pregnancy and in the 3rd quarter 21.8% in 2008). In the investigator's country, among the smokers of early pregnancy with the usual care, only 30% manage to stop during pregnancy. Maternal smoking during pregnancy is a clearly identified risk factor for the course of pregnancy and the unborn child. The measurement of carbon monoxide (CO) expired in pregnancy monitoring consultation is part of the recommendations of the consensus conference "Pregnancy and Tobacco" (ANAES, October 2004) and the parliamentary report on smoking by JL Touraine and D. Jacquat (Feb 2012). However, this recommendation has not entered the current practice. The research aims to justify the clinical relevance of this recommendation by demonstrating the positive impact of expired CO measurement on the rate of discontinuation during pregnancy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
102
An expired CO measurement will be performed by BabyCO and the result will be returned to the smoking pregnant woman by the consultant.
The nature of the samples taken during the delivery are: * maternal blood, * cord blood * placenta fragment
University Hospital, Limoges
Limoges, France
Smoking cessation on the date of birth
Evaluate the impact on maternal smoking cessation rate at birth of a strategy combining maternal expired CO measurement, restitution, and outcome comment initiated no later than at the 24th week of amenorrhea and conducted thoughout the whole pregnancy.
Time frame: Date of birth
Impact on maternal, placental and fetal exposure to the toxic and compounds of tobacco smoke.
Impact on maternal, placental and fetal exposure to the toxic and compounds of tobacco smoke measured in maternal, cordal blood and placenta by ICP-MS, GC-MS and LC-MS methods
Time frame: Date of birth
Impact on the intention of breastfeeding on the date of birth
Impact on the intention of breastfeeding on the date of birth evaluated by a questionnaire
Time frame: Date of birth
Predictive value of expired CO in relation to maternal-fetal exposure to these toxic and compounds
Determine the predictive value of expired CO in relation to maternal-fetal exposure to these toxic and compounds
Time frame: Date of birth
Maternal expired CO on the day of birth
Maternal expired CO on the day of birth
Time frame: Date of birth
Determinants of smoking cessation on the day of birth
Potential determinants of smoking cessation, including: age, parity, precariousness assessed by the EPICES score, history of smoking before pregnancy, expired CO measurement, etc.
Time frame: Date of birth
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