The purpose of this study is to assess the safety and efficacy of Timolol Maleate treatment for different depth of infantile hemangioma based on B-ultrasonography. Based on the depth of hemangioma, patients will be proactively allocated to two groups. And then, all patients in both groups will receive topical timolol treatment in the same protocol and dosage.
Primary: Describe the efficacy of 0.5% topical timolol maleate drops in different depth of infantile hemangioma as assessed through IB-ultrasound.
Study Type
OBSERVATIONAL
Enrollment
150
External use of 0.5% Timolol Maleate Drops for all patients in different depths of IH lesion.
Shanghai Ninth People's hospital, Shanghai Jiaotong University School of Medicine
Shanghai, Shanghai Municipality, China
RECRUITINGDepth of infantile hemangioma
At the beginning of treatment, the thickness of hemangioma was measured by b-mode ultrasound at each follow-up.
Time frame: through study completion, an average of 1 year
Color
The redness of lesion is measured by standard photography.
Time frame: through study completion, an average of 1 year
Dimensions
The dimension of lesion is measured by standard photography.
Time frame: through study completion, an average of 1 year
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