Avazzia-University of Texas Southwestern Medical Center-Tennant Biomodulator® PRO Perfusion Study

Inclusion Criteria: * Able to provide Informed Consent * Ankle Brachial Index (ABI) ≥ 0.5 (bedside ABI is acceptable for screening purposes as the formal imaging ABI may not be resulted prior to therapy) * Participant is a hospital in-patient for the duration of study procedures * One or more chronic lower extremity wounds that are located in the ankle area or below that has persisted a minimum of 30 days prior to the Screening visit * 18 years of age or older Exclusion Criteria: * Unable to provide informed consent * \<18 years of age * Participant has a demand-type cardiac pacemaker, implanted defibrillator or other implanted metallic or electronic device. * Participant has untreated osteomyelitis * Participant has active cellulitis * Participant has active charcot * Is pregnant or plans to become pregnant * Is nursing or actively lactating * Developmental disability/significant psychological disorder that in the opinion of the investigator could impair the participant's ability to provide informed consent, participate in the study protocol including untreated schizophrenia, bipolar disorder and psychiatric hospitalization within the last 2 years.