Effects of 3D-printed on Lower Extremity Biomechanics in Individuals With Knee Osteoarthritis

National Yang Ming Chiao Tung University15 enrolled

Overview

The purposes of this study are: (1) to determine the kinematics, kinetics, and muscle co-activation ratio of level walking and stair negotiation under three different conditions (shoes only, shoes embedded 3D printed insoles, and shoes embedded 5-degree lateral wedges), (2) to build a detailed patient-specific knee model via MR images and musculoskeletal model, then, evaluate the compressive forces acting on the medial aspect of the knee during level walking and stair negotiation.

This study is a cross-sectional study with patients serving as their own control. The investigators will recruit 20 patients with knee osteoarthritis. Using motion capture system, force plates, wireless EMG to capture the motion data of patients during walking and stair negotiation in each condition.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Medial Knee Osteoarthritis

Interventions

3D-printed foot orthosesDEVICE

3D printed foot orthoses with arch support

5 degrees lateral wedge insolesDEVICE

Insoles with a lateral inclination set at 5 degrees

Eligibility

Sex: ALLMin age: 50 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Medial knee OA (Kellgren-Lawrence grade I, II or III) according to clinical and radiological criteria of the American College of Rheumatology * Aged from 50 to 70 years Exclusion Criteria: * Neuromuscular illness (e.g., Parkinson disease, Neuropathy) * Predominant lateral or patella-femoral OA * Previous of planned hip or knee replacement * Hip or ankle arthritis * Rheumatoid arthritis * Unable to walk without a cane or walker * Unable to walk up and down the stairs

Locations (1)

National Yang-Ming University

Taipei, Taiwan

Outcomes

Primary Outcomes

Knee adduction moment during level walking and stair negotiation

Surrogate marker of medial knee loading. Using motion capture system data to calculate the knee adduction moment via inverse dynamics method.

Time frame: 10 minutes

Medial knee joint contact force during level walking and stair negotiation

Calculate the medial knee force to identify the change in medial knee loading by musculoskeletal model. The musculoskeletal model is driven by motion capture system data.

Time frame: 10 minutes

Muscle co-activation ratio during level walking and stair negotiation

Level of muscle co-activation measured by electromyography (EMG).

Time frame: 10 minutes

Secondary Outcomes

Knee flexion moment during level walking and stair negotiation

Surrogate marker of medial and lateral knee loading. Using motion capture system data to calculate the joint moments via inverse dynamics method. The calculated joint moments (N\*m) will be normalized by multiplying body weight (Newton) and leg length (meter).

Time frame: 10 minutes

Path of center of pressure during level walking and stair negotiation

The factor of affect the joint moments. Measured by force platform.

Time frame: 10 minutes

Lower limbs joint angles during level walking and stair negotiation

Lower limbs alignment, including hip, knee and ankle joints. Using motion capture system data to calculate the joint angles.

Time frame: 10 minutes

Data from ClinicalTrials.gov

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