Quadratus Lumborum Block : Effect on Acute Pain and Quality of Recovery After Laparoscopic Adrenalectomy

Peking Union Medical College Hospital25 enrolled

Overview

This prospective, randomized ,control study aims to compare the analgesic effect,quality of recovery, length of hospital stay ,et al. between single-injection QLB(quadratus lumborum block)+general anesthesia (GA) and general anesthesia (GA) alone in patients undergoing laparoscopic adrenalectomy.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

TRIPLE

Enrollment

Conditions

Pain Management Nerve Block Laparoscopic Adrenalectomy

Interventions

single-injection QLB(quadratus lumborum block)PROCEDURE

Inject 0.4ml/kg 0.5% ropivacaine between quadratus lumborum and psoas major without continuous local infusion Device: Ultrasound Scanner The curved (C1-5) probe of Ultrasound Scanner is used for scan Device: PAJUNK StimuLong Drug: single dose ropivacaine 0.4ml/kg 0.5% ropivacaine given immediately after the correct position of the tip of the needle has been verified.

Placebo controlPROCEDURE

Inject 0.4ml/kg saline between quadratus lumborum and psoas major without continuous local infusion Device: Ultrasound Scanner The curved (C1-5) probe of Ultrasound Scanner is used for scan Device: PAJUNK StimuLong Drug: single dose 0.4ml/kg 0.9% NS. given immediately after the correct position of the tip of the needle has been verified.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 18-70 yrs * American Society of Anesthesiologists physical statusⅠ-Ⅲ * Undergo laparoscopic adrenalectomy * Informed consent Exclusion Criteria: * A known allergy to the drugs being used * Coagulopathy, on anticoagulants * Analgesics intake, history of substance abuse * Participating in the investigation of another experimental agent * Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)

Locations (1)

Peking Union Medical College Hospital

Beijing, China

Outcomes

Primary Outcomes

pain numeric rating scale (NRS, 0-10)pain score at activity at 12 hours after surgery

Time frame: At 12hours after the surgery

Secondary Outcomes

The pain scores at rest determined by the numeric rating scale (NRS, 0-10)

Time frame: At 2,4, 8, 12,24 ,48,72hours after the surgery

incidence of postoperative nausea and vomiting (PONV)

Time frame: within 24 postoperative hours

ambulation time

Time frame: within5 days after surgery

time of restart anal exhaust

Time frame: within 5 days after surgery

Postoperative length of hospital stay

Time frame: up to2 weeks after surgery

patient's satisfaction with anesthesia and analgesia

use the Chinese version Bauer questionnaire to assess the patient satisfaction with anesthesia and analgesia

Time frame: 48 hours after surgery

The pain scores at activity determined by the numeric rating scale (NRS, 0-10)

Time frame: At 2,4, 8, 24 ,48,72hours after the surgery

Data from ClinicalTrials.gov

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