Clinical Study of Titrating PEEP of Different Methods on Right Heart Function

Southeast University, China30 enrolled

Overview

To observe the influence of different methods titrating PEEP on right heart function and pulmonary artery pressure in ARDS patients .

30 patients who diagnosed as ARDS were included in this study.Then set PEEP with respectively ARDS net 、EIT and Esophageal Pressure in Breathing Machine . Recorded diameter of right and left ventricular TAM TAPSE pulmonary artery pressure.Objective to evaluate the correlation between the level of PEEP in three methods and the right heart function and pulmonary artery pressure in ARDS patients .

Study Type

OBSERVATIONAL

Enrollment

Conditions

ARDS, Human

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients admitted to ICU diagnosed of modecate to severe ARDS (Berlin criteria) * Patients age between 18 years old and 80 years Exclusion Criteria: * Patients with chronic respiratory diseases such as COPD. * Ventilated because of oesophageal surgery in the previous 12months. * Patients who cannot obtain clear ultrasound images due to thoracic surgery ,massive pleural effusion. * Oesophageal bleeding in previous 30 days history of oesophageal varices. * Facial trauma and surgery.

Locations (1)

Zhongda Hospital

Nanjing, Jiangsu, China

RECRUITING

Outcomes

Primary Outcomes

the function of right heart and pulmonary artery pressure

Systolic Pulmonary Artery Pressure TAPSE or Tricuspid Annular Motion orTricuspid annular plane systolic excursion or right ventricular diameter or right left ventricular diameter ratio in diffrient PEEP

Time frame: 2018.4-2019.3

Central Contacts

Dutong Yue, Dr

CONTACT

15051887681 1475008526@qq.com

GuoFeng Mei, Dr

CONTACT

13813841261 13813841261@139.com

Data from ClinicalTrials.gov

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