Internet Delivered CBT for Olfactory Reference Syndrome

Volen Ivanov15 enrolled

Overview

The primary aim of the study is to test the feasibility and efficacy of, a manual based, Internet-delivered, cognitive behaviour therapy (CBT) for patients with Olfactory Reference Syndrome (ORS) who live in Sweden. The secondary aim is to investigate smell sensitivity and body odor in these ORS-patients.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Olfactory Reference Syndrome

Interventions

Cognitive behavioral therapyBEHAVIORAL

Cognitive behavioral therapy

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Primary diagnosis of ORS * Outpatients * Male or female * Signed informed consent * Have regular access to a computer with Internet access and skills to use the web Exclusion Criteria: * Not able to read or understand the basics of the ICBT self-help material * Psychotropic medication changes within two months prior to treatment * Completed CBT for ORS within last 12 months * Ongoing substance dependence or misuse * Lifetime bipolar disorder or psychosis * Suicidal ideation * Axis II diagnosis that could jeopardize treatment participation * Serious physical illness that will be an obstacle in ICBT * Other ongoing psychological treatments that could affect ORS symptoms * Epilepsia

Locations (1)

M46: Karolinska Universitetssjukhuset, Psykiatri Sydväst Stockholm, Huddinge, Sweden, 141 86

Stockholm, Sweden

Outcomes

Primary Outcomes

Yale-Brown Obsessive Compulsive Scale Modified for olfactory reference syndrome (ORS-YBOCS)

The instrument is a 12-item clinician-administered scale rating the severity of ORS symptoms during the past week. Each item is scored along a Likert scale ranging from 0 (least extreme) to 4 (most extreme), with higher total scores indicating more severe ORS symptoms (range 0-48).

Time frame: Change from baseline (week 0) to post-treatment (week 10).

Secondary Outcomes

Yale-Brown Obsessive Compulsive Scale Modified for olfactory reference syndrome - Self Report (ORS-YBOCS-SR)

The instrument is a12-item self-administered scale rating the severity of ORS symptoms during the past week. Each item is scored along a Likert scale ranging from 0 (least extreme) to 4 (most extreme), with higher total scores indicating more severe ORS symptoms (range 0-48).

Time frame: Change from baseline (week 0) to post-treatment (week 10).

The Montgomery Åsberg Depression Rating Scale - self report (MADRS-S)

Time frame: Change from baseline (week 0) to post-treatment (week 10).

Data from ClinicalTrials.gov

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