Postprandial Lipid Metabolism in Patients With Hypertriglyceridemia and Normo-lipidemic Controls: Medium Chain Fatty Acids (MCT) in Comparison to Long-chain, Saturated Fatty Acids (SFA) and Mono-unsaturated Fatty Acids (MUFA)

Ludwig-Maximilians - University of Munich13 enrolled

Overview

Postprandial lipid metabolism will be evaluated in patients with hypertriglyceridemia and normo-lipidemic controls; different fats will be used (saturated fatty acids, mon-unsaturated fatty acids and medium chain fatty acids) for the oral fat challenge.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

SINGLE

Enrollment

Conditions

Hypertriglyceridemia

Interventions

MCTOTHER

patients will receive fat load with MCT

SFAOTHER

patients will receive fat load with SFA

MUFAOTHER

patients will receive fat load with MUFA

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * hypertriglyceridemia (150 mg/dl-900 mg/dl) Exclusion Criteria: * Lipid lowering drugs or indication for Lipid lowering drugs * LDL-cholesterol \> 190 mg/dl * Diabetes mellitus

Locations (1)

University Munich

Munich, Germany

Outcomes

Primary Outcomes

postprandial hypertriglyceridemia

area under the curve following oral fat load

Time frame: 8 hours after fat meal

Data from ClinicalTrials.gov

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