Topical Calcipotriol Versus Narrowband Ultraviolet B in Treatment of Alopecia Areata

Aswan University Hospital60 enrolled

Overview

Alopecia Areata is a common condition. This study investigated the efficacy of calcipotriol versus Narrow Band Ultraviolet B in treatment of Alopecia areata and their effects on serum vitamin D3 levels.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Alopecia Areata

Interventions

CalcipotriolDRUG

Calcipotriol ointment (0.005%)

Narrow Band UVBDEVICE

NB-UVB (311nm) phototherapy

vitamin D3 levelDIAGNOSTIC_TEST

vitamin D3 (ng/ml)

Eligibility

Sex: ALLMin age: 14 YearsMax age: 40 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Alopecia Areata of scalp Exclusion Criteria: Other causes of alopecias including scarring alopecia, androgenic alopecia, telogen effluvium autoimmune diseases, pregnant and lactating females

Locations (1)

Aswan University Hospital

Aswān, Egypt

Outcomes

Primary Outcomes

Clinical improvement of Alopecia Areata After treatment As assessed by Severity of Alopecia tool (SALT) score

calculation of SALT score before and after treatment

Time frame: 3 months

Improvement of serum Vitamin D levels in (ng/ml) after treatment

measurement of serum vitamin D before and after treatment

Time frame: 3 months

Data from ClinicalTrials.gov

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