The aim of the study is to compare, during general anesthesia using neuromuscular blocking agent, the feasibility of a new mechanographic device (ITF handle and Visual ITF software) with a standard acceleromyographic device (TOF Watch SX) and also to assess its safety during the first 24 hours after surgery. The two devices will be studied simultaneously in each patient.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
15
Compare the pattern of neuromuscular blocking drug between two devices applied on the same patient during general anesthesia.
Chu de Poitiers
Poitiers, France
Delay of block installation between the injection and the disappearance of all the muscular contractions to stimulation by train of four
We compare the response to curare with one side a conventional TOF Watch SX monitor and other side Handle Isometric Thumb Force.
Time frame: Usefulness of non depolarizing muscle relaxant-induced muscle paralysis is limited at the surgery period and should be avoided once the surgery is completed. Therefore, all measurements are done during this time.
Clinical examination
Appearance of the wrist skin (for example: redness, irritations or marks)
Time frame: the first 24 postoperative hours
Clinical examination
Wrist pain
Time frame: the first 24 postoperative hours
Characteristics of maintenance curarization
Value of the post-tetanus count at the time of administration of an extra bolus of rocuronium and the number of muscle contractions in response to a four-train stimulation
Time frame: Usefulness of non depolarizing muscle relaxant-induced muscle paralysis is limited at the surgery period and should be avoided once the surgery is completed. Therefore, all measurements are done during this time.
Characteristics of decurarization during spontaneous recovery phase
Delay of the gear ratio from train of four to 25; 75 and 90%.
Time frame: Usefulness of non depolarizing muscle relaxant-induced muscle paralysis is limited at the surgery period and should be avoided once the surgery is completed. Therefore, all measurements are done during this time.
When the TOF ratio will be greater than 0.9 on the TOF Watch side, the degree of residual paralysis will be assessed on the ITF side using 100 Hz tetanus stimulation repeated 5 times at 2 minutes interval
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The response of theses tetanus stimulations will be compared with the one observed before myorelaxant administration but after induction of anesthesia
Time frame: Usefulness of non depolarizing muscle relaxant-induced muscle paralysis is limited at the surgery period and should be avoided once the surgery is completed. Therefore, all measurements are done during this time.