However, local anesthetic agents can produce analgesia for a limited time when used as a single injection. Bupivacaine is a local anesthetic that has an immediate action on pain by blocking peripheral afferents. However, as the ideal analgesic, the drug must cover the whole postoperative period (≥ 24 hours); therefore, bupivacaine is usually combined with many adjutants to provide long-lasting post-arthroscopy analgesia.
Intr-articular drug administration has gained popularity because of its simplicity and efficacy in achieving anesthesia for diagnostic and operative arthroscopy and for providing postoperative analgesia .although the knee joint has been examined most commonly, arthroscopy of other joints such as shoulder, ankle, wrist, metatarsophalangeal and temporomandibular joints is being increasingly used. Intra-articular installation of local anesthesia during arthroscopic procedures has been used by many orthopedic surgeons to provide pain relief after surgery.The aim of this study was to evaluate the analgesic efficacy of intra-articular dexamethasone versus fentanyl added as an adjuvant to bupivacaine in patients undergoing knee arthroscopic surgery
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Enrollment
87
The patient were received an intra-articular injection of 18ml bupivacaine 0.25% added to 8mg dexamethasone.
The patient were received an intra-articular injection of 1 ug/kg fentanyl added to 18ml of 0.25% bupivacaine.
Patients were received an intra-articular injection of 2ml isotonic saline added to 18ml of 0.25% bupivacaine.
Mohamed A Sultan
Al Mansurah, DK, Egypt
Mansoura University
Al Mansurah, Eastern, Egypt
Duration of postoperative analgesia
Time to the first request of pethidine in minutes within the first 24 hours postoperatively
Time frame: for 24 hour after surgery
Total analgesic requirement
Total analgesic requirement of pethidine will be recorded during the first 24 hours following surgery
Time frame: for 24 hour after surgery
Mean arterial blood pressure
Mean arterial blood pressure measured in mm Hg and assessed at 1,2,4,6,8,12,18 and 24 hours following the discharge of the patient from the operating theatre.
Time frame: At 1,2,4,6,8,12,18 and 24 hours postoperatively.
Heart rate
Heart rate will be measured in beats/minute and assessed at 1,2,4,6,8,12,18 and 24 hours following the discharge of the patient from the operating theatre.
Time frame: At 1,2,4,6,8,12,18 and 24 hours postoperatively.
Pain score
Measured with visual analogue score(VAS):0=no pain and 100=worst imaginable pain measured at 1,2,4,6,8,12,18 and 24 hours
Time frame: measured at 1,2,4,6,8,12,18 and 24 hours postoperatively.
Patients' satisfaction
satisfaction score from 1 to 4; as 4=Excellent ,3=good ,2=satisfactory and 1=poor will be measured after 24 hours.
Time frame: for 24 hour after surgery
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