Effect of Modified Time-restricted Feeding in Preventing Progression of Non-Alcoholic Fatty Liver Disease (NAFLD).

The University of Texas Health Science Center, Houston40 enrolled

Overview

The purpose of the study is to examine the effects of modified time-restricted feeding and conventional dietary approaches in motivated obese fatty liver patients on biochemical markers, imaging studies, and anthropometric measurements.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Non-Alcoholic Fatty Liver Disease

Interventions

Conventional dietBEHAVIORAL

The conventional diet arm will be asked to consume a hypocaloric diet, and they will be allowed to eat at any time of the day with no time restriction.

Modified Time-restricted FeedingBEHAVIORAL

The modified time-restricted feeding arm will be asked to consume any food but will be asked to consume this food for only a 9 hour daytime period.

Physical activityBEHAVIORAL

At least 30 minutes of physical activity per day 5 times per week.

Eligibility

Sex: ALLMin age: 8 YearsMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Motivated obese fatty liver patients aged 8 -18yrs with ALT \>80 Exclusion Criteria: * Patients with metabolic disorders, * On certain medications (i.e., amiodarone, corticosteroids, methotrexate, select antipsychotics /antidepressants, HAART, valproic acid), * Kwashiorkor * Alcohol abuse, * Rapid surgical weight loss, * History of parenteral nutrition and * Hepatitis C.

Locations (1)

The University of Texas Health Science Center at Houston

Houston, Texas, United States