Osteaoarticular infection due to C. acnes are known to be of late onset, causing chronic infection possibly pauci-symptomatic. Osteaoarticular infection due to C. acnes represents a diagnostic challenge, since C. acnes is slow and difficult to grow, and can also be considered a contaminant.A 16S universal PCR bacteriological diagnosis has been proposed but is lacking of sensitivity. A specific C. acnes PCR was developed in 2010, but is not used routinely.
Study Type
OBSERVATIONAL
Enrollment
6
patients having a prosthesis infection with C.acnes identified by specific PCR
Hospices Civils de Lyon
Lyon, France
Rate of diagnostic delay
time between surgery and detection of C. acnes by PCR
Time frame: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption
rate of radiologic signs
prosthesis loosening or not
Time frame: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption
rate of duration of antibiotherapy
measures of duration of the antibiotherapy
Time frame: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption
rate of use of this diagnostic
descriptions of patients managed with this diagnostic
Time frame: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption
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