Feeding Premature Infants During Non-invasive Respiratory Support

Rambam Health Care Campus100 enrolled

Overview

A randomized control trial comparing bolus gavage feeds to continuous feed among premature infants supported by non-invasive respiratory support

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

100

Conditions

Premature Infant Non-invasive Respiratory Support

Interventions

Length of feedingOTHER

Feeds will be given via nasogastric tube over 15-30 min versus 2 hr

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Infants \<1500gr, on non-invasive respiratory support * Feeding\>20 ml/kg/day Exclusion Criteria: * Major congenital malformations * Unstable infants because of sepsis, central nervous system, cardiac or other significant morbidities * Gastrointestinal morbidity such as spontaneous intestinal perforation (SIP) and necrotising enterocolitis (NEC).

Locations (1)

Rambam Medical Center

Haifa, Israel

RECRUITING

Outcomes

Primary Outcomes

Oxygenation instability as documented by oxygen saturation histograms

Time frame: before dischatge home at an average of 40 weeks gestation

Time to full feeds (TFF) defined as full enteral gavage feeding of 150 cc/Kg/day

Time frame: before dischatge home at an average of 40 weeks gestation

Secondary Outcomes

Respiratory-length of respiratory support

Time frame: before dischatge home at an average of 40 weeks gestation

Incidence of Necrotising enterocolitis (NEC) as defined by the medical team

Time frame: before dischatge home at an average of 40 weeks gestation

Central Contacts

Liron Borenstein-Levin, MD

CONTACT

04-7774125 liron.boren@gmail.com

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.