The aim of the present project is to evaluate the frequency of distant metastases and clinically relevant relapse and mortality, respectively, of aNEN (Neuroendocrine Neoplasms of the Appendix) measuring 1 - 2 cm. The investigators hypothesize that the mortality rate of aNET (Neuroendocrine Tumors of the Appendix) measuring 1 - 2cm is less than 1%. Furthermore, the investigators hypothesize that regional lymph node metastases of aNET measuring 1 - 2 cm are clinically not relevant and are not associated with reduced survival. The investigators therefore hypothesize that oncological right-sided hemicolectomy has no impact on long-term survival after complete resection of aNET measuring 1 - 2 cm and that the malignant potential quo ad vitam of these tumors is lower than the risk of oncological hemicolectomy.
Study Type
OBSERVATIONAL
Enrollment
278
Histopathological review
UHIBerne
Bern, Switzerland
Clinically relevant relapse of aNET measuring 1 - 2 cm in a population based manner
Time frame: 10 years
Clinically relevant mortality of aNET measuring 1 - 2 cm in a population based manner
Time frame: 10 years
Frequency of distant metastases in aNET measuring 1-2 cm
Time frame: 10 years
Association of histological risk factors in aNET measuring 1 - 2 cm and qualifying for oncological right-sided hemicolectomy according to ENETS guidelines with the occurrence of regional lymph node and distant metastases
Time frame: 10 years
Relationship between regional lymph node metastasis and survival in patients with aNET measuring 1 - 2 cm
Time frame: 10 years
Long-term survival after complete resection of aNET measuring 1 - 2 cm with or without oncological right-sided hemicolectomy
Time frame: 10 years
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