Although angiographic embolization has been introduced for preoperative management of spine metastases in 1975 and is suggested today by many authors in the management of such pathologies, it needs to be confirmed by RCT. It is a minimally invasive procedure, not free from complications. The recent meta-analyzes, due to the limited number of patients included are not exhaustive about the effectiveness of embolization in the reduction of the intraoperative bleeding, especially in the context of poor / moderate metastasis vascularization. We want to evaluate the efficacy of preoperative angiographic embolization of intermediate / poor vascularized spine metastases in reducing intraoperative blood loss during excision surgery.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
100
Angiographic embolization
Giancarlo Facchini
Bologna, Italy
RECRUITINGIntraoperative blood loss
volume (ml) of intraoperative blood loss volume aspirated from operative field (ml) + differential weight gauze at the end of surgery - dry gauze weight with 1g blood conversion = 0.948ml
Time frame: during procedure
Concentration of Hemoglobin pre / post-operative
Time frame: 24 hours
volume of transfused blood (ml)
Time frame: intraoperatively
Correlation between primary tumor and vascularization
Time frame: during angiographic procedure
correlation between the type of primary tumor and blood losses
Time frame: 24 hours
technical evaluation of the final result of embolization (total - 100%, subtotal 90-80% and partial 70-50%) in relation to blood losses
Time frame: during angiographic procedure
evaluation of operative time, from incision to end of suture
Time frame: during procedure
incidence of complications related to transfusions;
Time frame: during hospitalization
duration of the hospitalization in ICU
Time frame: during hospitalization
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