Using Isosorbide Mononitrate in Reducing Time in Induction of Labor in Post Date Women

Abdelrahman Ali Fadel Youssef Mohamed100 enrolled

Overview

We will compare between using isosorbide mononitrate together with misoprostol versus the misoprostol alone in induction of labor in postdate women

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

100

Conditions

Induction of Labor

Interventions

Isosorbide mononitrateDRUG

Administration of isosorbide mononitrate vaginaly together with misoprostol in induction of labor in postdate women

MisoprostolDRUG

Used intravaginally to ripe the cevix in induction of labor

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * age (20-35 yrs) * single fetus * gestational age \> 40weeks * not in labor * bishop score \< 7 * no medical disorder Exclusion Criteria: * Gestational age ≤40 weeks * patient with a ripe cervix * rupture of membranes * suspected chorioamnionitis * placenta previa * history of major uterine surgery * hypertonic uterine pattern * contraindicated to receive PG * fetal malpresentation * multiple pregnancy * intrauterine growth retardation * women with any general medical disorder

Locations (1)

Ain Shams maternity hospital

Cairo, Egypt

RECRUITING

Outcomes

Primary Outcomes

The duration of induction to active phase interval

Measure the time between the beginning of the induction to enter the active phase of labor

Time frame: 12 weeks

Data from ClinicalTrials.gov

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