Multiple Sclerosis (ME) is a degenerative, inflammatory and autoimmune demyelinating disease of the central nervous system, characterized by demyelination due to inflammation and degeneration of the myelin sheaths enveloping nerves of the eye, periventricular grey matter, brain, spinal cord and brainstem. The symptoms associated with MS include symptomatic fatigue, muscle weakness, ataxia, mobility and balance problems or cognitive problems. Moderate intensity strength training has been shown to improve strength and mobility in persons with MS. It was suggested that whole-body vibration training (WBVT) is effective to improve muscle strength, such as resistance training, resulting from both neural and structural adaptations. On the other hand, traditional strength training in hypoxia has garnered much attention. This method has shown improvements in isometric strength and increases in muscle size.
* Crossover. * 13 patients with multiple sclerosis were recruited. * Patients performed two sessions: whole-body vibration training in normoxia condition and whole-body vibration in hypoxia condition.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
13
Whole-body vibration training in hypoxia and normoxia condition
Universidad Católica San Antonio
Murcia, Spain
Maximal Voluntary Isometric Contraction of Knee Extension
Time frame: Immediately before the training sessions
Maximal Voluntary Isometric Contraction of Knee Extension
Time frame: Immediately after the training sessions
Rate of Force Development
Time frame: Immediately before the training sessions
Rate of Force Development
Time frame: Immediately after the training sessions
Central Activation Ratio
Time frame: Immediately before the training sessions
Central Activation Ratio
Time frame: Immediately after the training sessions
Biomechanical study of the walk by video recording
Kinematic analysis of knee and ankle angles during walking
Time frame: Immediately before the training sessions
Biomechanical study of the walk by video recording
Kinematic analysis of knee and ankle angles during walking
Time frame: Immediately after the training sessions
Biomechanical study of the walk by video recording
Stride amplitude during walking
Time frame: Immediately before the training sessions
Biomechanical study of the walk by video recording
Stride amplitude during walking
Time frame: Immediately after the training sessions
Spasticity
Pendulum test
Time frame: Immediately before the training sessions
Spasticity
Pendulum test
Time frame: Immediately after the training sessions
Rate of Perceived Exertion
RPE Scale 6-20
Time frame: Immediately before the training sessions
Rate of Perceived Exertion
RPE Scale 6-20
Time frame: Immediately after the training sessions
Walking speed
Test 10 m-walks
Time frame: Immediately before the training sessions
Walking speed
Test 10 m-walks
Time frame: Immediately after the training sessions
Static balance
Romberg Test with eyes open and closed. Analysis with force plates
Time frame: Immediately before the training sessions
Static balance
Romberg Test with eyes open and closed. Analysis with force plates
Time frame: Immediately after the training sessions
Muscle oxygenation in soleus
MOXY's
Time frame: Immediately before the training sessions
Muscle oxygenation in soleus
MOXY's
Time frame: Immediately after the training sessions
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