Precision of OCT and OCTA-based Ocular Measurements

Optovue144 enrolled

Overview

Precision of OCT- and OCTA-based Ocular Measurements

The purpose of this study is to assess precision of measurements of vascular structures and the anatomical structures of the posterior pole of the eye based on OCTA and OCT scans in normal subjects, glaucoma patients, and retina patients, and to assess measurements of corneal layers based on corneal OCT scans in normal subjects and cornea patients.

Study Type

OBSERVATIONAL

Enrollment

144

Conditions

Normal Eyes and Ocular Pathology

Interventions

SD-OCTDEVICE

Spectral Domain Optical Coherence Tomography for non-invasive, light-based, cross-sectional imaging of ocular structures

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Normal - No glaucoma or treatment to lower IOP or retinal pathology for posterior imaging; No contact lens wear, dry eye, anterior pathology or ocular surgery for corneal imaging. * Glaucoma - Have glaucoma and no history of other retinal pathology. * Retina - Have retinal pathology and no history of glaucoma or treatment to lower IOP. * Cornea - Contact lens wear or corneal condition such as dry eye, KCN, or post refractive surgery. Exclusion Criteria: * Normal - Unable to complete required exams; Clinical finding of posterior pathology or VA worse than 20/40 for posterior imaging; Clinical findings of corneal condition for corneal imaging. * Glaucoma - Unable to complete required exams; Clinical signs of retinal pathology. * Retina - Unable to complete required exams. * Cornea - Unable to complete required exams.

Locations (1)

AMA

Marysville, Ohio, United States

Outcomes

Primary Outcomes

Repeatability and Reproducibility Standard Deviation of ocular measurements

calculated value minus the measured value

Time frame: Day 1

Secondary Outcomes

Repeatability and Reproducibility Coefficient of Variation of ocular measurements

maximum difference that is likely to occur between repeated measurements

Time frame: Day 1

Data from ClinicalTrials.gov

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