Covered stents (CS) are a potentially lifesaving treatment for grade III coronary perforation but delivery can be challenging, and the long-term durability and safety including risk of acute stent thrombosis are unknown. The GNOCCI study aims to evaluate long term outcomes after coronary perforation including patients treated with covered stents.
Covered stents (CS) are a potentially lifesaving treatment for grade III coronary perforation but delivery can be challenging, and the long-term durability and safety including risk of acute stent thrombosis are unknown. Using an electronic data base, details of all coronary perforations are identified and anonymised patient and procedural details are recorded.Procedural major adverse cardiac events (pMACE) are defined as a composite of death, myocardial infarction, stroke, target vessel revascularization or cardiac surgery within 24 hours of the index procedure. Two independent cardiologists adjudicate outcomes and differences in opinion are resolved by consensus with a third cardiologist. The overall GNOCCI study aims are: 1. Evaluate procedural and long term outcomes after coronary perforation 2. Long term safety and clinical events in patients treated with covered stents.
Study Type
OBSERVATIONAL
Enrollment
161
Insertion of covered coronary stent as part of standard care
Golden Jubilee National Hospital
Glasgow, United Kingdom
Procedural major adverse cardiac events (pMACE)
Defined as a composite of death, myocardial infarction, stroke, target vessel revascularization or cardiac surgery
Time frame: 24 hours of the index procedure.
MACE
death, myocardial infarction, stroke, target vessel revascularization or cardiac surgery
Time frame: Up to 10 years
Stent thrombosis
ARC definite or probable
Time frame: Up to 10 years
Unsuccessful covered stent deployment
Attempted covered stent insertion without sealing of perforation, defined by case review of two independent cardiologists from source files
Time frame: 24 hours of the index procedure.
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