The purpose of this study is to investigate the positive effects of red ginseng extract on intestinal bacterial changes and immunity, free radicals, antioxidant capacity, and autonomic nervous system changes in age of 40\~75 men and women with climacteric symptoms for 24 weeks.
A screening test is conducted for those who have agreed in writing with a detailed explanation of the purpose of this study and research methods, and then a person who meets the selection / exclusion criteria is selected. Give a registration number to the person selected as the subject through the screening, and take one pack of the product (3g) once a day for 24 weeks in a human body application test. Prior to taking the registration number (1Day), the efficacy evaluation items and the safety evaluation items are carried out. At the 24 weeks after the starting point of taking the product of human application test, the evaluation items are conducted through outpatient visits.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
53
Take one pack of the product (3g) once a day for 24 weeks
Changes in gut microbiota at 24 weeks vs baseline
Time frame: 24 weeks
Changes in Total Oxidant Status(TOS in µmol/L) at 24 weeks vs baseline
Time frame: 24 weeks
Changes in Total Antioxidant Status(TAS in mmol/L) at 24 weeks vs baseline
Time frame: 24 weeks
Changes in Natural Killer(NK) cell activity at 24 weeks vs baseline
Time frame: 24 weeks
Changes in Heart rate variability at 24 weeks vs baseline
Time frame: 24 weeks
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